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KMID : 1160620140190040333
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Preventive Nutrition and Food Science
2014 Volume.19 No. 4 p.333 ~ p.342
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Relationship between Blood Mercury Level and Risk of Cardiovascular Diseases: Results from the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) 2008-2009
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Kim Young-Nam
Kim Young-A
Yang Ae-Ri
Lee Bog-Hieu
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Abstract
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Limited epidemiologic data is available regarding the cardiovascular effects of mercury exposure. The pur-pose of this study was to determine the relationship between mercury exposure from fish consumption and car-diovascular disease in a nationally representative sample of Korean adults using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV 2008∼2009). Survey logistic regression models accounting for the com-plex sampling were used to estimate the odds ratios (OR) adjusted for fish consumption frequency, age, education, in-dividual annual income, household annual income, body mass index (BMI), waist circumference (WC), alcohol con-sumption status, and smoking status. The mean blood mercury level in the population was 5.44 ?g/L. Trends toward in-creased blood mercury levels were seen for increased education level (P=0.0011), BMI (P＜0.0001), WC (P＜0.0001), and fish (i.e., anchovy) consumption frequency (P=0.0007). The unadjusted OR for hypertension in the highest blood mercury quartile was 1.450 [95% confidential interval (CI): 1.106∼1.901] times higher than that of the lowest quartile. The fish consumption-adjusted OR for hypertension in the highest blood mercury quartile was 1.550 (95% CI: 1.131∼2.123) times higher than that of the lowest quartile, and the OR for myocardial infarction or angina in the highest blood mercury quartile was 3.334 (95% CI: 1.338∼8.308) times higher than that of the lowest quartile. No associations were observed between blood mercury levels and stroke. These findings suggest that mercury in the blood may be associated with an increased risk of hypertension and myocardial infarction or angina in the general Korean population.
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KEYWORD
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blood mercury levels, cardiovascular disease, KNHANES, fish consumption
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