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KMID : 1160620160210030187
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Preventive Nutrition and Food Science
2016 Volume.21 No. 3 p.187 ~ p.196
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Supplementation of a Fermented Soybean Extract Reduces Body Mass and Prevents Obesity in High Fat Diet-Induced C57BL/6J Obese Mice
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Lee Jae-Yeon
Aravinthan Adithan
Park Young-Shik
Hwang Kyo-Yeol
Seong Su-Il
Hwang Kwon-tack
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Abstract
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Obesity is a growing health problem that many countries face, mostly due to the consumption of a Westernized diet. In this present study we observed the effects of a soybean extract fermented by Bacillus subtilis MORI (BTD-1) containing 1-deoxynojirimycin against high fat diet-induced obesity. The results obtained from this study indicated that BTD-1 reduced body weight, regulated hepatic lipid content and adipose tissue, and also affected liver antioxidant enzymes and glucose metabolism. These results suggest that administration of BTD-1 affects obesity by inhibiting hyperglycemia and free radical-mediated stress; it also reduces lipid accumulation. Therefore, BTD-1 may be potentially useful for the prevention of obesity and its related secondary complications.
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KEYWORD
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obesity, fermented soybean extracts, glucose metabolism, antioxidant enzymes, lipid accumulation
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