KMID : 1160620200250040449
|
|
Preventive Nutrition and Food Science 2020 Volume.25 No. 4 p.449 ~ p.456
|
|
Study of Flavonoid/Hydroxypropyl-¥â-Cyclodextrin Inclusion Complexes by UV-Vis, FT-IR, DSC, and X-Ray Diffraction Analysis
|
|
Kim Ji-Sang
|
|
Abstract
|
|
|
The objective of this study was to investigate characterization of inclusion complexes of flavonoids with hydroxypropyl-¥â-cyclodextrin (HP-¥â-CD). The inclusion complexes of flavonoids with HP-¥â-CD was prepared by the freezedrying method and its characterization was investigated by different analytical techniques including ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy (FT-IR), differential scanning calorimetry, and X-ray diffractometry. The catechin/HP-¥â-CD complex exhibited the highest encapsulation efficiency (83.37%), followed by epicatechin/HP-¥â-CD (81.51%), morin hydrate/HP-¥â-CD (81.38%), and quercetin/HP-¥â-CD (81.16%). The inclusion complexes of HP-¥â- CD showed a decrease in the absorption of flavonoids with a small shift (?2 nm) of the ¥ëmax, while similar to the characteristic absorption peak of flavonoids. However, the FT-IR spectra of the flavonoid/HP-¥â-CD inclusion complexes did not display any features that were like the pure flavonoids, although the spectra were very similar to that of HP-¥â-CD. The melting point of flavonoids disappeared, and the thermal properties of HP-¥â-CD were altered following formation of the inclusion complex between flavonoids and HP-¥â-CD, resulting in a shift in the melting peak.
|
|
KEYWORD
|
|
flavonoids, hydroxypropyl-¥â-cyclodextrin, inclusion complex
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|