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KMID : 1188320200140060707
Gut and Liver
2020 Volume.14 No. 6 p.707 ~ p.726
Clinical Guidelines for Drug-Related Peptic Ulcer, 2020 Revised Edition
Joo Moon-Kyung

Park Chan-Hyuk
Kim Joon-Sung
Park Jae-Myung
Ahn Ji-Yong
Lee Bong-Eun
Lee Jeong-Hoon
Yang Hyo-Joon
Cho Yu-Kyung
Bang Chang-Seok
Kim Beom-Jin
Jung Hye-Kyung
Kim Byung-Wook
Lee Yong-Chan
Abstract
Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcer were previously developed in 2009 with the collaboration of the Korean College of Helicobacter and Upper Gastrointestinal Research and Korean Society of Gastroenterology. However, the previous guidelines were based mainly upon a review of the relevant literature and expert opinion. Therefore, the guidelines need to be revised. We organized a guideline Development Committee for drug-related peptic ulcer under the auspices of the Korean College of Helicobacter and Upper Gastrointestinal Research in 2017 and developed nine statements, including four for NSAIDs, three for aspirin and other antiplatelet agents, and two for anticoagulants through a de novo process founded on evidence-based medicine that included a literature search and a meta-analysis, A consensus was reached through the application of the modified Delphi method. The primary target of these guidelines is adult patients undergoing long-term treatment with NSAIDs, aspirin or other antiplatelet agents and anticoagulants. The revised guidelines reflect the expert consensus and is intended to assist clinicians in the management and prevention of druginduced peptic ulcer and associated conditions.
KEYWORD
Peptic ulcer, Non-steroidal anti-inflammatory agents, Antiplatelet agent, Anticoagulants, Guideline
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