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KMID : 1188520110070010060
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Korean Journal of Clinical Oncology
2011 Volume.7 No. 1 p.60 ~ p.65
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Diagnostic value of preoperative sonographic evaluation for axillary lymph node metastases in breast cancer patients
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Han Dong-Il
Gwak Geum-Hee
Han Se-Hwan
Cho Hyun-Jin
Yang Keun-Ho
Bae Byung-Noe
Kim Ki-Whan
Kim Ji-Young
Park Kyeong-Mee
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Abstract
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Purpose: The aim of this study was evaluate predictive value of preoperative sonography for the evaluation of axillary lymph node metastases in breast cancer patients.
Materials and Methods: The study included 226 patients who underwent curative surgery between Jan. 2008 ~ Dec. 2010 at Inje University Sanggye Paik Hospital. We analyzed preoperative sonographic findings of axillary lymph nodes and compared the finding with postoperative histologic results of axillary lymph nodes evaluation.
Results: When we compared preoperative sonographic evaluation of metastatic lymph node with final histological results, the sensitivity of sonographic evaluation was 81.3% and specificity was 77.5%. False positive rate was 10.7% and false negative rate was 35.8%. The accuracy of preoperative sonographic evaluation of lymph node metastasis was 78.7%. Primary tumor size was the only significant predictive factor for lymph node metastasis on multivariate analysis.
Conclusion: preoperative sonographic evaluation of axillary lymph node had limited value with moderate accuracy. High false-negative rate of preoperative sonography indicates that preoperative sonography cannot replace intraoperative sentinel node evaluation at this stage.
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KEYWORD
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axillary lymph nodes metastases, breast ca, breast sonography
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