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KMID : 1188520110070020044
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Korean Journal of Clinical Oncology
2011 Volume.7 No. 2 p.44 ~ p.49
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Prognostic Factors of StageⅡ Rectal Cancer
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Hwang Bo-Hyun
Park Ji-Won
Park Sung-Chan
Kim Sun-Young
Baek Ji-Yeon
Kim Dae-Yong
Chang Hee-Jin
Choi Hyo-Seong
Oh Jae-Hwan
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Abstract
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Background: In stage Ⅱ rectal cancer, it has remained controversial whether patients get the benefit from adjuvant treatment after curative resection. The aim of this study is to evaluate the prognostic factors of stage Ⅱ rectal cancer.
Methods: From October 2000 to December 2008, 200 patients with stage Ⅱ rectal cancer underwent surgery at National Cancer Center. Univariate and multivariate survival analyses were performed to determine the prognostic factors in stage Ⅱ rectal cancer.
Results: In stage Ⅱ rectal cancer, 5-year overall survival and disease free survival were 89.2% and 89.0%, respectively. For overall survival, there was no significant prognostic factor in multivariable analysis. For diseasefree survival, tumor differentiation and circumferential resection margin were significant prognostic factors in multivariable analysis.
Conclusion: Tumor differentiation and circumference resection margin are independent prognostic factors in disease free survival of stage Ⅱ rectal cancer. Adjuvant treatment may be considered in patients with these factors
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KEYWORD
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rectal cancer, stage Ⅱ, prognostic factor, survival
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