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KMID : 1188520120080020010
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Korean Journal of Clinical Oncology
2012 Volume.8 No. 2 p.10 ~ p.15
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What is an optimal nutritional index for hepatocellular carcinoma during early perioperative period after hepatic resection?
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Kim Sang-Hwa
Lim Jin-Hong
Kim Sung-Hoon
Lee Su-Ji
Lee Ho-Sun
Lee Jae-Gil
Kim Choong-Bai
Kim Kyung-Sik
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Abstract
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After hepatic resection, a synthetic liver function is often deteriorated, and ascites have been occasionally developed. Because of these limitations, this study is designed to validate the optimal nutritional index.
We retrospectively reviewed medical records of sixty-five patients who underwent hepatectomy for hepatocellular carcinoma. Body weight, Body Mass Index (BMI) and laboratory parameters were compared at preoperative day and postoperative day 7.
Patients consist of fifty-two males and thirteen females and average age is 56.2±9.9 years old. Forty-four patients had resected more than three segments, and twelve had resected 2 segments and nine had resected only one segment or received a wedge resection. According to preoperative BMI, there were two underweight (BMI < 18.5), twenty-two normal, nineteen overweight, and twenty-two obese (BMI>=27.5). After the surgery, lymphocyte count, total protein, albumin, BUN, Cholesterol, Prealbumin statistically significantly increased (p=0.00 & p=0.00). However, BMI and change in Body weight do not show statistically significant data (p=1.91, p=8.23).
The degree of inflammation may have a significant influence in nutrition evaluation scale. Therefore, a new method of nutritional evaluation that can adjust degree of inflammation is needed to accurately evaluate the nutrition scale after hepatectomy.
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KEYWORD
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Hepatectomy, Nutritional assessment, Nutritional index, Prealbumin
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