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KMID : 1188520130090020076
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Korean Journal of Clinical Oncology
2013 Volume.9 No. 2 p.76 ~ p.79
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Geriatric anesthesia
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Noh Gyu-Jeong
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Abstract
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As a result of improvements in health care, nutrition, and general living standards, the average life expectancy and elderly population is increased worldwide. Aging is associated with a universal and progressive loss of functional reserve and degenerative changes in all organ systems. Although physiologic compensation for age-related changes may be adequate in most geriatric patients, the functional reserve of organ systems is reduced, and susceptibilities to stress- and disease-induced organ system decompensation can occur. Anticipating the interactions between underlying diseases, limited end-organ reserve, and perioperative stress should aid physicians in providing the best perioperative care possible. We review the age-related physiologic changes in organ systems and pharmacokinetic and pharmacodynamic changes of anesthetics in elderly surgical patients.
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KEYWORD
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Geriatric, Anesthesia, Physiologic changes
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