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KMID : 1188520200160010025
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Korean Journal of Clinical Oncology
2020 Volume.16 No. 1 p.25 ~ p.32
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Poorly differentiated thyroid carcinoma: An institutional experience
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Choi Seok-Won
Lee Joon-Hyop
Kim Yun-Young
Chung Yoo-Seung
Choi Sang-Tae
Kim Na-Rae
Kang Jin-Mo
Park Heung-Kyu
Chun Yong-Soon
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Abstract
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Purpose: The incidence of poorly differentiated thyroid carcinoma (PDTC) is extremely low among thyroid cancers and there is no standardized treatment guideline for it. In this study, we have analyzed PDTC patients and reviewed their clinicopathological features.
Methods: Data of PDTC patients from our institution are collected through the electronic medical database. We analyzed them by several parameters such as basic demographics, presenting symptom, preoperative cytology results, associated pathology, surgical results, surgery type, and distant metastasis.
Results: We collected 23 cases in our institution. Apart from two patients who were transferred to another hospital upon diagnosis, all 21 operated cases are analyzed. The parameters we studied were age, sex, presenting symptoms, distant metastasis and pathological features such as tumor size, associated pathology, predominant pattern and so on. We also provided descriptive analyses according to the type of presentation and treatment; patients with distant metastasis, juvenile cancer, and concurrent hyperthyroidism. Furthermore, we provided different cases in which the initial surgical plans differed.
Conclusion: We present 21 cases of PDTC patients and clarify their clinicopathological features. Despite some limitations, this study may shed light for future research regarding treatment of PDTC patients.
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KEYWORD
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Thyroid neoplasms, Neoplasm metastasis, Surgery
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