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KMID : 1200820030030010040
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Oriental Pharmacy and Experimental Medicine
2003 Volume.3 No. 1 p.40 ~ p.45
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Effect of Bamboo salt-pro on carries-inducing properties of Streptococcus mutans
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Shin Hye-Young
You Hyeon-Hee
Shin Tae-Yong
Kim Hyung-Min
You Yong-Ouk
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Abstract
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We studied the effect of Bamboo salt-pro on the growth and acid production of S. mutans. The growth of S.mutans was reduced by the presence of the Bamboo salt-pro (1 mg/ml) and NaCl (1 mg/ml) significantly, and the positive control group (1 % of NaF) also exhibited antibacterial activity significantly. Bamboo salt-pro (1 mg/ml) reduced the rate of acid production by S. mutans. Bamboo salt alone did not demonstrate such a reduction in acid production at the concentration of 1 mg/ml. The inhibitory action of Bamboo salt-pro on acid production was found at a concentration of 1 mg/ml, but bamboo salt alone was not at a concentration of 1 mg/ml. In addition, we investigated the anti-inflammatory effect of Bamboo salt-pro on human mast cell line HMC-1. Bamboo salt-pro (0.1 and 0.01 mg/ml) inhibited significantly the secretion of inflammatory cytokine, tumor necrosis factor-a with , respectively. Our results suggest that Bamboo salt-pro importantly contributes to the prevention or treatment of periodontitis and other oral diseases and inflammatory diseases.
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KEYWORD
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Bamboo salt-pro, S. mutans, Periodontitis, Tumor necrosis
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