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KMID : 1200820030030010046
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Oriental Pharmacy and Experimental Medicine
2003 Volume.3 No. 1 p.46 ~ p.50
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Action of enzyme food, Green Life Enzyme on systemic and local anaphylaxis
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Moon Phil-Dong
Na Ho-Jeong
Kim Hyung-Min
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Abstract
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We studied the inhibitory effect of Green Life Enzyme (GLE) on compound 48/80-induced anaphylactic response in a murine model. GLE inhibited compound 48/80-induced systemic anaphylactic shock at the dose of 10 g/kg by 87.5%. When GLE was given as pre-treatment at concentrations ranging from 0.01 to 1.0 g/kg, it inhibited passive cutaneous anaphylaxis activated by anti-dinitrophenyl (DNP) IgE. In addition, GLE (0.1 mg/ml) inhibited anti-DNP IgE-induced tumor necrosis production from mast cells by 69% compared to saline value. These results indicate that GLE may possess anti-anaphylactic and anti-inflammatory activity.
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KEYWORD
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Green Life Enzyme, Systemic anaphylactic shock, Passive cutaneous anaphylaxis, Tumor necrosis
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