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KMID : 1200820040040020070
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Oriental Pharmacy and Experimental Medicine
2004 Volume.4 No. 2 p.70 ~ p.76
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Post-coital antiimplantation and pregnancy interruption potency of the seeds of Crotalaria juncea Linn
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Malashetty Vijaykumar B.
A. Sharanabasappa
Patil Saraswati B.
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Abstract
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Petroleum ether, benzene and alcohol extracts of the seeds of C. juncea were tested for antiimplantation and pregnancy interruption activities in female albino rats. Of these three extracts, the alcohol extract was found to be the most effective in causing antiimplantation and pregnancy interruption activities. These adverse effects on fertility are reversible upon withdrawal of the extract treatments. The alcohol extract was found to possess estrogenic activity. After subjecting to preliminary phytochemical screening, the alcohol extract showed positive tests for alkaloids, steroids, glycosides, saponins, flavonoides, fixed oils, phenols and tannins.
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KEYWORD
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Crotalaria juncea, Rat, Antiimplantation, Pregnancy, Estrogenic activity
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