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KMID : 1200820040040030187
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Oriental Pharmacy and Experimental Medicine
2004 Volume.4 No. 3 p.187 ~ p.195
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Free radical scavenging activity of some Bangladeshi plant extracts
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Uddin Shaikh Jamal
Shilpi Jamil Ahmad
Delazar AndAbbas
Nahar Lutfun
Sarker Satyajit Dey
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Abstract
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A number of plants from different geographical origins have been shown to possess antioxidant activity. Some of them have been developed as natural antioxidant formulations for food, cosmetic and other applications. Bangladeshi flora is a rich source of a range of plant species, many of which are medicinal plants, and have been used in the preparations of the Unani and Ayurvedic traditional medicines. There are no, or just a few, reports on any systematic screening of the extracts of Bangladeshi plants for free radical scavenging activity using DPPH assay available to date. As part of our on-going search for biological activity in Bangladeshi plants, Kadam (Anthocephalus chinensis), Goran (Ceriaps decandra), Swarnalata (Cuscuta reflexa), Gab (Diospyros peregrina), Sundari (Heritiera fomes), Dhundul (Xylocarpus granatum) and Possur (Xylocarpus mekongensis) have been selected for the assessment of their free radical scavenging activity, and studies on the contents of alkaloids, anthraqunones, flavonoids and tannins in these extracts. Most of these species have been used in traditional medicine in Bangladesh and other countries for the treatment of various illnesses ranging from common cold to cancer. All extracts, except the methanol extract of Cuscuta reflexa, displayed significant free radical scavenging activity in the DPPH assay values within the range of . Among these extracts, the methanol extract of Xylocarpus granatum exhibited the most potent activity and that of Cuscuta reflexa had the least activity . While none of these plants showed positive tests with Dragendorff’s reagent, presence of low to moderate amounts of phenolic compounds, e.g. anthraquinones, flavonoids and tannins was evident in all of these plants, except for the methanolic extracts of C. reflexa and the barks of D. peregrina, which did not display any evidence for the presence of flavonoids and anthraquinones, respectively.
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KEYWORD
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Convolvulaceae, Ebenaceae, Meliaceae, Rhizophoraceae, Rubiaceae, Sterculiaceae, DPPH assay, Natural antioxidant
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