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KMID : 1200820040040040235
Oriental Pharmacy and Experimental Medicine
2004 Volume.4 No. 4 p.235 ~ p.242
Hypoglycemic, antistress, anxiolytic, and nootropic activity of roots of Rubia cordifolia Linn
Kasture Veena S.

Kasture Sanjay B.
Abstract
The alcoholic extract of dried roots of Rubia cordifolia dose dependently reduced blood sugar level in alloxan treated rats. The extract also reduced ulcer index, plasma corticosterone in cold restrain stressed rats in dose related manner. The mice treated with alcoholic extract of Rubia cordifolia spent more time in the open arm of the elevated plus maze indicating anxiolytic activity. The extract also antagonized the amnesic effect of scopolamine in mice as indicated by reduced transfer latency in the elevated plus maze. Thus the plant bears potential for use in diabetes, stress, anxiety, and dementia.
KEYWORD
Rubia cordifolia, Hypoglycemic, Anxiolytic, Antistress, Nootropic
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