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KMID : 1200820060060040293
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Oriental Pharmacy and Experimental Medicine
2006 Volume.6 No. 4 p.293 ~ p.299
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Regions in China identification and quality control of radix Codonopsis by chemical fingerprint: Evaluation of lobetyolin from different cultivated
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Chou Gui X
Gao Qiu T
Li Jun
Duan Ran
Cheung Anna WH
Chu Glanice KY
Jiang Zhi Y
Dong Tina TX
Tsim Karl WK
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Abstract
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By using high-performance liquid chromatography-photodiode array detection, a simple and accurate chromatographic fingerprint method was developed for the identification of Radix Codonopsis (roots of Codonopsis) from different sources. Eighteen herbs of Codonopsis at different habitats in China, including roots from Codonopsis pilosula, Codonopsis pilosula var. modesta and Codonopsis tangshen were analyzed by the fingerprint. The amount of lobetyolin was calibrated, which was found to be more consistent in roots of Codonopsis pilosula as compared to that of Codonopsis pilosula var. modesta and Codonopsis tangshen. Having the fingerprint results, hierarchical clustering analyses were performed to classify the eighteen herbs into three groups: Codonopsis pilosula, Codonopsis pilosula var. modesta and Codonopsis tangshen. This clustering analysis agrees very well with the pharmacognostic identification result, and which could be used as a tool in the quality control of Radix Codonopsis.
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KEYWORD
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Radix Codonopsis, Codonopsis pilosula, Codonopsis pilosula var modesta, Codonopsis tangshen, Fingerprint, Chinese medicine, Quality assurance
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