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KMID : 1200820070070010100
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Oriental Pharmacy and Experimental Medicine
2007 Volume.7 No. 1 p.100 ~ p.102
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Short Communication Antinociceptive activity of Avicennia officinalis
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Shahid IZ
Karmakar D
Sadhu SK
Ahmed F
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Abstract
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The crude ethanol extract of leaves of Avicennia officinalis Linn. (Family: Avicenniaceae) was screened for its antinociceptive activity. The extract produced significant writhing inhibition in acetic acid-induced writhing in mice at the oral dose of 250 and 500 mg/kg body weight (P < 0.001) comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight. The result tends to suggest the antinociceptive activity of the extract.
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KEYWORD
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Antinociceptive, Avicennia officinalis, Avicenniaceae
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