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KMID : 1200820070070040385
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Oriental Pharmacy and Experimental Medicine
2007 Volume.7 No. 4 p.385 ~ p.389
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Preliminary antioxidant, antibacterial and cytotoxic activities of Momordica charantia Linn leaf
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Rahman Shafiur
Iqbal Asif
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Abstract
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We undertook the present study to evaluate different pharmacological as antioxidant, antibacterial and cytotoxic activities of the crude ethanolic extract of Momordica charantia (Family: Cucurbitaceae) leaves. The antioxidant property of the extract was assessed by 1, 1-diphenyl-2-picryl hydrazyl free radical scavenging assay. The extract showed antioxidant activity where was about was about for standard drug ascorbic acid. The extract showed a broad spectrum of antibacterial activity against all the tested gram positive and gram-negative bacteria where Staphylococcus epidermidis, Staphylococcus aureus, Salmonella typhi and Shigella dysenteriae were prominent. And the zones of inhibition were ranging from 8-15 mm for all the tested bacteria. Its cytotoxic property was evaluated by brine shrimp lethality bioassay. The extract showed significant lethality and the value was .
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KEYWORD
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Momordica charantia, Antioxidant activity, 1, 1-diphenyl-2-picryl hydrazyl, Antibacterial activity, Cytotoxic activity
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