KMID : 1200820080070050527
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Oriental Pharmacy and Experimental Medicine 2008 Volume.7 No. 5 p.527 ~ p.533
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Analgesic and anti-inflammatory effect of the aqueous extract of root of Angelica Dahurica
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Choi In-Ho
Lim Hyung-Ho Song Yun-Kyung Lee Jin-Woo Kim Young-Sick Ko Il-Gyu Kim Ki-Jeong Shin Mal-Soon Kim Khae-Hawn Kim Chang-Ju
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Abstract
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Angelica dahurica (Umbelliferae) grows in China, Japan, Russia, and Korea. The root of Angelica dahurica has been used as a traditional folk medicine to treat headache and toothache. In this study, the effects of the aqueous extract of Angelica dahurica on acetic acid-induced abdominal pain, carrageenan-induced edema, and thermal hyperalgesia were investigated using mice and rats. The present results showed that the aqueous extract of Angelica dahurica inhibited acetic acidinduced abdominal pain in mice and reduced carrageen-induced edema in rats. The present study showed that the aqueous extract of Angelica dahurica possesses anti-inflammatory and analgesic effects.
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KEYWORD
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Angelica dahurica, Analgesic and anti-inflammatory effect, Edema, Thermal pain
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