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KMID : 1200820080070050527
Oriental Pharmacy and Experimental Medicine
2008 Volume.7 No. 5 p.527 ~ p.533
Analgesic and anti-inflammatory effect of the aqueous extract of root of Angelica Dahurica
Choi In-Ho

Lim Hyung-Ho
Song Yun-Kyung
Lee Jin-Woo
Kim Young-Sick
Ko Il-Gyu
Kim Ki-Jeong
Shin Mal-Soon
Kim Khae-Hawn
Kim Chang-Ju
Abstract
Angelica dahurica (Umbelliferae) grows in China, Japan, Russia, and Korea. The root of Angelica dahurica has been used as a traditional folk medicine to treat headache and toothache. In this study, the effects of the aqueous extract of Angelica dahurica on acetic acid-induced abdominal pain, carrageenan-induced edema, and thermal hyperalgesia were investigated using mice and rats. The present results showed that the aqueous extract of Angelica dahurica inhibited acetic acidinduced abdominal pain in mice and reduced carrageen-induced edema in rats. The present study showed that the aqueous extract of Angelica dahurica possesses anti-inflammatory and analgesic effects.
KEYWORD
Angelica dahurica, Analgesic and anti-inflammatory effect, Edema, Thermal pain
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