|
KMID : 1200820080070050564
|
|
Oriental Pharmacy and Experimental Medicine
2008 Volume.7 No. 5 p.564 ~ p.568
|
|
|
Protective effects of Polygala tenuifolia on ischemia-induced 4 vessel occlusion in rats
|
|
Kim Young-Ock
Kim Su-Kang
Cho Ah-Rang
Chung Joo-Ho
|
|
|
Abstract
|
|
|
|
The root of Polygala tenuifolia Willd (PT) is known to have neuroprotective effects and as an antidementic herb in Chinese and Japanese traditional medicine. We examined potential neuroprotective effects of PT using the 4-vessel occlusion model in rats. In this study, the efficacy of PT for the prevention of neuronal damage and for the reduction of memory impairment was investigated. The results indicate that PT confers significant neuroprotection especially for ischemic hippocampal neurons.
|
|
|
KEYWORD
|
|
|
Polygala tenuifolia, Neuroprotective, Ischemia, Hippocampus
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|