|
KMID : 1200820080080020187
|
|
Oriental Pharmacy and Experimental Medicine
2008 Volume.8 No. 2 p.187 ~ p.191
|
|
|
Analgesic and antidiarrhoeal activities of Treama orientalis Linn. in mice
|
|
Uddin Sarder Nasir
Uddin Khan Mohammad Ahsan
Ahmed Firoz
|
|
|
Abstract
|
|
|
|
Trema orientalis Linn. is commonly grown in many parts of Bangladesh. Its leaves have been used for analgesic and anti-diarrhoeal activity in traditional medicine. This study evaluates the potential analgesic and anti-diarrhoeal activity of methanol and aqueous extracts of leaves in experimental acetic acid induced writhing and castor oil induced diarrhoea in mice. The aqueous extract of leaves showed significant (P < 0.001) analgesic effect in acetic acid induced writhing in mice at a dose of 500 mg/kg body weight In castor oil induced antidiarrhoeal screening both extract increased latent period (P < 0.025) and decrease the number of stool (P < 0.025) at the dose of 500 mg/kg body weight comparable with that of the standard drug loperamide. The results provide a support for the use of this plant in traditional medicine and suggest its further investigation.
|
|
|
KEYWORD
|
|
|
Analgesic, Antidiarrhoea, Trema orientalis Linn., Extract
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|