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KMID : 1200820080080040423
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Oriental Pharmacy and Experimental Medicine
2008 Volume.8 No. 4 p.423 ~ p.429
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Anti-inflammatory and analgesic activities of methanol extract of Triphala - a poly herbal formulation
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Prabu D.
Kirubanandan S.
Ponnudurai K.
Nappinnai M.
Jinu Alin J.S.
Renganathan S.
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Abstract
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Ayurveda, an ancient System of Indian Medicine, has recommended a number of drugs from indigenous plant sources for the treatment of inflammation. To evaluate the anti-inflammatory and analgesic activities of methanol extract of Triphala were investigated in Wister albino rats and mice. The methanol extract of Triphala were found to encompass substantial anti-inflammatory effect in acute and sub-acute models and analgesic effect. Animal models of carrageenan induced edema and cotton pellet induced granuloma in albino rats were used. Extract of 200 mg/kg shows significantly reduced paw edema. Analgesics activity of Triphala with 200 mg/kg shown by significant reduction of writhing. These report shows to support the use methanol extract of Triphala in relieving inflammation and pain.
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KEYWORD
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Triphala, anti-inflammatory, analgesic, rat, mice
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