KMID : 1200820090090020182
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Oriental Pharmacy and Experimental Medicine 2009 Volume.9 No. 2 p.182 ~ p.185
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Preliminary antimicrobial and cytotoxic activities of Amoora cucullata extractives
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Rahman Mohammad S.
Rashid Mohammad A.
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Abstract
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Amoora cucullata (Meliaceae), a mangrove plant, has folkloric reputation as a medicinal agent in Bangladesh. In this study, the n-hexane, ethyl acetate and methanolic extracts of the stem bark of this plant were subjected to microbiological investigation and brine shrimp lethality bioassay. In case of antimicrobial screening, the ethyl acetate and methanolic extracts appeared to be potent in terms of both zone of inhibition and spectrum of activity showing the average zones of inhibition 8 - 14 mm and 9 - 16 mm, respectively. In the brine shrimp lethality bioassay, the methanolic extract demonstrated highest cytotoxicity having of , whereas the ethyl acetate and n-hexane extract showed of 7.943 and , respectively.
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KEYWORD
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Amoora cucullata, Antimicrobial, Cytotoxicity, Disc diffusion, Brine shrimp lethality bioassay
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