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KMID : 1200820110110020119
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Oriental Pharmacy and Experimental Medicine
2011 Volume.11 No. 2 p.119 ~ p.122
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Anthelmintic activity of Clerodendrum viscosum
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Das Jayanta Kumar
Choudhury S.
Adhikary S.
Das B.
Samanta S.
Mandal S. C.
Dey S. P.
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Abstract
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The juice of the fresh leaves of Clerodendrum viscosum is widely used in the treatment of helminthiasis in folklore medicine. In this present study we have investigated the folklore claim methodically and scientifically. The ethanolic and aqueous extracts of leaves and roots of the plant are tested against Pheretima posthuma & Ascardia galli to ascertain their anthelmintic potential. All the extracts showed significant anthelmintic activity in dose dependent manner; the ethanolic extract of root at a dose of 200 mg/ml exhibited better anthelmintic activity than the reference drug, Piperazine citrate (10 mg/ml) against both type of worms.
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KEYWORD
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Clerodendrum viscosum, Anthelmintic activity, Ethanolic root& leaf extract, Aqueous root & leaf extract, Pheretima posthuma, Ascardia galli
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