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KMID : 1200820110110030177
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Oriental Pharmacy and Experimental Medicine
2011 Volume.11 No. 3 p.177 ~ p.181
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Boswellic acid suppresses cyclophosphamide induced chromosomal damage in mice
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Ganguly Kuntal
Jagadeesh N. V.
Singh Rakesh
Thippeswami B. S.
Taranalli Ashok D.
Kulkarni Anandrao R.
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Abstract
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This study was performed to determine whether Boswellic acid suppresses genotoxicity induced by cyclophosphamide in mice. Genotoxicity was induced by the administration of cyclophosphamide (50 mg/kg) in swiss albino mice and was measured by counting the number of micronuclei and observing chromosomal aberration. In test group Boswellic acid was given in the dose of 200 mg/kg and various chromosomal aberration and formation of micronuclei were observed. Boswellic acid in dose of 200 mg/kg significantly (P?
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KEYWORD
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Boswellic acid, Genotoxicity, Micronucleus, Chromosomal aberration
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