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KMID : 1200820120120010015
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Oriental Pharmacy and Experimental Medicine
2012 Volume.12 No. 1 p.15 ~ p.34
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Study of clinically used and recently developed antimycobacterial agents
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Asif Mohammad
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Abstract
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Tuberculosis is one of most pervasive, respiratory transmitted diseases and has spread to every corner of the globe. According World Health Organization report, as much as one-third of the world’s population is currently infected by tuberculosis. There has been considerable interest in the currently used antimycotubercular compounds to inhibit or prevent mycobacterium species. These mycobacterium species have developed resistant against currently used drugs and produced toxic effect on long duration of therapy. These agents have different structure and almost all compounds having heterocyclic ring having one and more than one heteroatoms. These observations have been guiding for the currently used and newly developed antitubercular agents that possess potent antimicrobial activity and their side effects, activity against multi drug resistance MDR, XDR mycobacterium, and also in patient co-infected with HIV/AIDS.
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KEYWORD
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Antitubercular agents, Mycobacterium, Multi drug resistance, Side effects, Co-infection
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