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KMID : 1200820120120020099
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Oriental Pharmacy and Experimental Medicine
2012 Volume.12 No. 2 p.99 ~ p.106
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Eugenia jambolana seed extract supplementation attenuates cardiac and hepatic oxidative stress and pathophysiological changes in hypercholesterolemic rats
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Sankhari Jayanta M.
Jadeja Ravirajsinh N.
Thounaojam Menaka C.
Devkar Ranjitsinh V.
Ramachandran A. V.
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Abstract
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The present study was aimed at evaluating protective role of Eugenia jambolana seed extract (EJSE) on high cholesterol diet (HCD) induced hyperlipidemia/hypercholesterolemia amounting to cardiac and hepatic oxidative stress. Serum markers of cardiac and hepatic damage, total lipid profile (serum, tissue and feces), lipid peroxidation, antioxidant status and histopathological changes in cardiac and hepatic tissue have been assessed in control, HCD fed and HCD+EJSE treated (100 mg/kg BW, p.o.) rats. It was observed that co-supplementation of EJSE to HCD fed rats significantly (p?
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KEYWORD
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Eugenia jambolana, Hyperlipidemia, Oxidative stress, Histopathology
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