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KMID : 1200820120120020123
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Oriental Pharmacy and Experimental Medicine
2012 Volume.12 No. 2 p.123 ~ p.127
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Phytochemical investigation and simultaneous study on antipyretic, anticonvulsant activity of different leafy extracts of smilax zeylanica Linn
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Jena Prabhat Kumar
Dinda Subas Chandra
Ellaiah P.
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Abstract
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The present study was carried out to investigate the anti-pyretic and anticonvulsant activity of petroleum ether, ethyl acetate, n-butanol and ethanol extracts of Smilax zeylanica Linn, leaves using experimental animal models. The extracts were screened for alkaloids, steroids, proteins, flavanoids, saponins, mucilage, carbohydrates, tannins, fats and oils. Anti-pyretic activity was evaluated using the brewer’s yeast-induced pyrexia in rats. The extracts in dose levels of 200 mg/kg orally were used for anti-pyretic studies. The petroleum ether extracts of leaves of Smilax zeylanica Linn produced significant (P?
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KEYWORD
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Smilax zeylanica, Anti-pyretic, Anticonvulsant, Brewer’s yeast induced pyrexia, Strychnine Hydrochloride, Clonazepam.
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