|
KMID : 1200820130130010029
|
|
Oriental Pharmacy and Experimental Medicine
2013 Volume.13 No. 1 p.29 ~ p.34
|
|
|
Evaluation of diabetic gastroparesis effect of Musa sapientum L. bark juice by reducing the level of oxidative stress
|
|
Darvhekar Vaibhav M.
Tripathi Alok S.
Jyotishi Shriramji G.
Mazumder Papiya Mitra
|
|
|
Abstract
|
|
|
|
Musa sapientum L. (Musaceae) a medicinal plant, is indicated for the treatment of various diseases including Diabetes in folklore medicine. The purpose of this study is to investigate the effect of Musa sapientum (MS) bark juice in Diabetic gastroparesis and in-vivo antioxidant effect in animal model. Diabetes was induced in rats by administering alloxan (120 mg/kg) in saline solution and housed for 6?8 week. Assessment of diabetes was done by GOD-POD method. The effects of MS bark juice (100 ml/kg) on gastric emptying time, intestinal transit time, contractility of fundus, pylorus and gastric acid secretion were observed in alloxan induced chronic diabetic rats. In addition the effect of MS bark juice on the tissue homogenate, oxidative stress parameters was evaluated like Lipid peroxidation (LPO), Superoxide Dismutase (SOD), Catalase (CAT) and Reduced Glutathione (GSH). MS bark juice significantly (p?
|
|
|
KEYWORD
|
|
|
Diabeties, Musa sapientum, Oxidative stress, Gastroparesis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|