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KMID : 1200820130130020121
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Oriental Pharmacy and Experimental Medicine
2013 Volume.13 No. 2 p.121 ~ p.126
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Evaluation of anti-inflammatory, analgesic, antipyretic and antiulcer activity of Punarnavasava: an Ayurvedic formulation of Boerhavia diffusa
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Gharate Manisha
Kasture Veena
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Abstract
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Punarnavasava, an Ayurvedic liquid dosage form containing self generated alcohol is commonly used to treat inflammatory conditions and edema. In the present study, we evaluated anti-inflammatory, analgesic, antipyretic, and antiulcer activity of three different brands of Punarnavasava. The formulation significantly inhibited carrageenan-induced rat paw edema, cotton pellet-induced granuloma, formalin-induced paw licking, yeast induced hyperpyrexia and pyloric ligated ulcers in rats. The study concludes that Punarnavasava has anti-inflammatory, central as well as peripheral antinociceptive, antipyretic and antiulcer activity and thus justifies its use in inflammatory conditions.
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KEYWORD
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Boerhavia diffusa, Yeast, Carrageenan, Formalin, Punarnavasava
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