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KMID : 1200820130130020159
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Oriental Pharmacy and Experimental Medicine
2013 Volume.13 No. 2 p.159 ~ p.164
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Central depressant activity of ethanol extract of Nymphaea alba rhizome in mice
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Bose Anindya
Ray Sarbani Dey
Sahoo Moumita
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Abstract
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Ethanol extract of the of rhizome of Nymphaea alba, at graded doses was investigated for the central depressant activity of the ethanol extract of rhizome. The behavioral effect of the extract (75, 150 and 300 mg/kg) was evaluated using diazepam induced sleep test, hole-board test, beam walking assay, staircase test, open field test and elevated plus maze assay, all in mice. The findings of this study suggest that the extract of N. alba rhizome contains some bioactive principles that are sedative in nature.
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KEYWORD
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Ethanol, Central, Depressant, Sedative, Rhizome
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