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KMID : 1200820130130030181
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Oriental Pharmacy and Experimental Medicine
2013 Volume.13 No. 3 p.181 ~ p.189
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Anti-inflammatory and antioxidant activities of ethanolic leaf extract of Brownlowia tersa (L.) Kosterm
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Hossain Hemayet
Jahan Ismet Ara
Howlader Sariful Islam
Shilpi Jamil Ahmed
Dey Shubhra Kanti
Hira Arpona
Ahmed Arif
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Abstract
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The present study was designed to investigate the inflammatory and antioxidant activities of ethanolic leaf extract of Brownlowia tersa (L.) Kosterm. The anti-inflammatory activity of leaf extract was studied using carrageenan and histamine-induced rat paw edema test at different doses (200 and 400 mg/kg body weight). DPPH free radical scavenging, nitric oxide scavenging, reducing power, Fe++ ion chelating ability and total phenolic content were used for determining antioxidant activities. The extract, at the dose of 400 mg/kg, showed a significant anti-inflammatory activity (P?
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KEYWORD
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Brownlowia tersa, Anti-inflammatory, DPPH free-radical scavenging, Nitric oxide radical scavenging, Reducing power, Total phenolic
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