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KMID : 1200820130130040307
Oriental Pharmacy and Experimental Medicine
2013 Volume.13 No. 4 p.307 ~ p.317
Sedative & anxiolytic studies of Capparis Zeylanica Linn. root extract
Mishra Sunil Kumar

Singh P. N.
Dubey S. D.
Abstract
HPTLC study confirms the presence of stigmasterol (0.51?¡¾?0.02 % w/w) and stachydrine (0.161?¡¾?0.01 % w/w) in ethanolic Capparis Zeylanica root extract (EECZ). The sedative effect of the EECZ (100?400 mg/kg, p.o.) was evaluated using pentobarbitone-induced sleep and exploratory board tests while the anxiolytic effect was evaluated at the same dose levels, using elevated plus maze (EPM), open field test (OFT) and light and dark box shuttle tests. EECZ produced significant (p?
KEYWORD
Sedative, Anxiolytic activity, Capparis zeylanica, Pentobarbitone-induced sleep test, Exploratory board test, Elevated plus maze test, Open field test
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