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KMID : 1200820140140010007
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Oriental Pharmacy and Experimental Medicine
2014 Volume.14 No. 1 p.7 ~ p.13
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Preclinical evaluation of Vallaris solanacea (roth) kuntze stem for its antiulcer and antioxidant activity in wistar albino rats
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Das S. K.
Pansuriya P. V.
Shukla S. T.
Gohil K. J.
Roy S. P.
Choudhury A.
Sutariya V. N.
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Abstract
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In the present study we evaluated the antiulcer and antioxidant activity of methanolic extract from stem of the plant Vallaris solanacea (roth) Kuntze using various experimental models in Wister albino rats. The methanolic extract was prepared for evaluation of antiulcer activity with dose [3.2 milligram (mg)/kilogram (kg) and 6.4 mg/kg] by using models?pylorus ligation (PL) and ethanol induced gastric ulcer in rats. Antioxidant activity was evaluated by estimation of lipid peroxidation and catalase activity in the ethanol induced gastric ulcer model in rats. The results obtained from present study revealed that Vallaris solanacea methanolic extract (VSME) decreases the ulcer index significantly (p?
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KEYWORD
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Antioxidant, Ranitidine, Antiulcer, Pylorus ligation, Vallaris solanacea
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