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KMID : 1200820140140040363
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Oriental Pharmacy and Experimental Medicine
2014 Volume.14 No. 4 p.363 ~ p.367
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Comparative study of antidiarrheal activity of methanol extracts from leaf and fruit of Pandanus odoratissimus Linn
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Rahman Khalilur
Islam Fokhrul
Barua Soumitra
Rahman Masudur
Sayeed Mohammed Abu
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Abstract
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Pandanus odoratissimus, a perennial, large shrub or small tree, has multifarious medicinal uses. The purpose of the present study was to evaluate the antidiarrheal effects of methanol extracts obtained from leaf and fruit of P. odoratissimus. The methanol extracts from the leaf and fruit of P. odoratissimus were evaluated for the antidiarrheal activity in rats. The effects of the extracts on defecation, intestinal transit and intestinal fluid accumulation (enteropooling) were assessed in castor oil-induced diarrhea. Oral administration of leaf and fruit extracts at 200 and 400 mg/kg exhibited significant (P?
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KEYWORD
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Antidiarrheal, Castor oil, Enteropooling, Intestinal transit, Pandanus odoratissimus
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