KMID : 1200820150150030173
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Oriental Pharmacy and Experimental Medicine 2015 Volume.15 No. 3 p.173 ~ p.181
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Clinical efficacy of a herbo-mineral Unani formulation in scabies: an open-label randomized controlled study
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Rahman Jameelur
Farooqi Akhtar H. Sultana Arshiya Rahman Khaleequr Rahman Ateequr
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Abstract
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To compare the efficacy of a herbo-mineral Unani formulation with benzyl benzoate in scabies. A parallel, prospective, open-labeled, standard-controlled, randomized trial was conducted in ZVM Unani College, Pune. Patients were randomized to receive topical application of either test formulation (n?=?30) (P. corylifolia, C. anthelminticum, C. tora and sulphur) or 25 % benzyl benzoate (n?=?30) respectively for 3 days. The primary and secondary outcomes were change in clinical grading of scabies lesions and intensity of itching respectively. In the present study, 86.67 and 90 % patients were cured in the test and control group respectively. At third follow up, itching severity score mean between the groups was statistically insignificant (P?=?0.66). At third follow-up mean itching severity score within group comparison from the baseline in both groups were statistically significant (P?0.0001). No adverse effects were noted. The test formulation was as effective as benzylbenzoate in alleviating scabies.
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KEYWORD
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Benzylbenzoate, Herbo-mineral formulation, Randomized controlled trial, ScabiesUnani medicine
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