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KMID : 1200820150150030207
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Oriental Pharmacy and Experimental Medicine
2015 Volume.15 No. 3 p.207 ~ p.215
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Pharmacological investigations of organic crude fractions of Dysophylla auricularia
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Nur Tanzina
Islam Torequl
Alam Syedul
Chowdhury M. Mohi Uddin
Melo Cavalcante Ana Amelia Carvalho
Freitas Rivelilson Mendes
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Abstract
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The aim of this present study is to investigate pharmacological activities of organic crude fractions of Dysophylla auricularia. For this organic fractions namely - ethanol, chloroform and n-hexane have been investigated for antimicrobial, anti-diarrheal, anti-inflammatory and membrane stabilization, α-glycosidase inhibitory and antipyretic activities. Results suggest that in the antimicrobial sensitivity study, ethanol and chloroform fractions produced inhibition zones with the ranges of 12 to 20 mm and 7 to 21 mm, respectively; where they strongly inhibited the growth of Shigella sonnei, Escherichia coli, Shigella dysenteriae and Microsporum sp. Crude fractions also revealed the presence of antidiarrheal, antiinflammatory and membrane stabilization, anti-amylase as well as antipyretic activities. In conclusion, it should be mentioned that D. auricularia may have one of the good sources for phytotherapy.
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KEYWORD
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Dysophylla auricularia, Crude, Organic fractions, Pharmacological
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