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KMID : 1200820170170010019
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Oriental Pharmacy and Experimental Medicine
2017 Volume.17 No. 1 p.19 ~ p.27
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A comparative study of two unani regimens in diabetic vulovaginal candidiasis
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Fatima Syeda Shahida
Sultana Shazadi
Sultana Arshiya
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Abstract
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To compare the efficacy of two Unani regimen in diabetic vulovaginal candidiasis (VVC). A prospective, randomized, single-blind, comparative trial was conducted at Nizamia Tibbia College. Group A (n = 23) medicine included 100 ml of Joshanda [Ushba Desi (5 g) and Tukhme Hayat (5 g)] with 3 g Sufuf [Mur Makki (1 g), Afsanteen (2 g), and Nagandbabari (3 g)] orally twice daily half an hour before meal. Locally, douche (Aab Barg Bakayan (5 g) and Sufuf Katha (1 g) followed by humul [Roghan Neem (10 ml), Luab Gheegawar (2 g) and Sufuf Zard Chobb (1 g)] was given daily once. Group B (n = 23) received 100 ml of aforementioned Joshanda with 3 g sufuf [Kutki Siyaha (2 g), Kali Zeeri (2 g) and Tukhme Kasni (2 g)] orally twice daily half an hour before meal. Locally, douche (Gulanar (5 g) and Barg babool 5 (g)] was given daily once. Both groups received the treatment for 10 days for three consecutive months. The primary outcomes included change in vaginal discharge and wet mount test. The secondary outcomes included other clinical features of VVC and blood glucose level. The results were analyzed. Group A and B showed absence of vaginal discharge and fungal spores/hyphae in 91.30% and 86.95% respectively, statistically not significant (P = 0.3), whereas pre- and post-test comparison was statistically significant in both groups (P < 0.001). Inter-group comparison was statistically non significant (P > 0.05) for remission of other clinical features and blood glucose level, whereas pre- and post-test comparison showed statistically significant difference in both groups (P < 0.001). Both groups were equally effective for the treatment of diabetic VVC.
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KEYWORD
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Diabetes mellitus, Vulvovaginal candidiasis, Abnormal vaginal discharge, Unani medicine
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