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KMID : 1200820170170040309
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Oriental Pharmacy and Experimental Medicine
2017 Volume.17 No. 4 p.309 ~ p.313
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Herbal medicine Radix Scutellariae quality improved by exposure of the fresh root to high temperature
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Fu Xiaoying
Guo Huimin
Cong Wei
Du Hongwei
Meng Xiang-Cai
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Abstract
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Approximately 1200 years ago, the close association between the quality of medicine and the producing area was well known in China. Recent work has shown conclusively that the quality of herbal medicine is influenced by unfavorable conditions, but the exact cause remains unclear and is a difficult problem in research on herb resources. Fresh roots of S. baicalensis were exposed to temperatures of 35 °C ~ 55 °C, and the H2O2 level remained relatively inflexible. The superoxide dismutase (SOD) and catalase (CAT) activities remained stable at 35 °C and 45 °C but decreased on day 1 at 55 °C. The excess ROS due to the high temperatures must be removed by another pathway. Our study reported that the phenylalanine ammonia-lyase (PAL) activities rose. The fresh roots were exposed to 55 °C for 2 days, the baicalin increased by 38.5%, the wogonoside by 24.1%, and the baicalein by 37.0%. This method can substantially improve the quality of Radix Scutellariae.
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KEYWORD
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Enzymatic antioxidant system, Flavonoids, Radix Scutellariae, Reactive oxygen species, Secondary metabolite
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