Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.
KMID : 1200820180180020115
Oriental Pharmacy and Experimental Medicine
2018 Volume.18 No. 2 p.115 ~ p.125
Fungal endophytes of an endemic plant Humboldtia brunonis wall. of western Ghats (India) and their antimicrobial and DPPH radical scavenging potentiality
Sheik Sana

Chandrashekar K. R.
Abstract
Endophytic fungi associated with leaf and stem samples of Humboldtia brunonis Wall, a dominant myrmecophyte, commonly known as ¡®hasige mara¡¯, endemic to the South Western Ghats of India were enumerated from two sites viz. Charmadi and Mangalore University arboretum and tested for antimicrobial activity. Aspergillus sp., Curvularia clavata, Curvularia pallescens, Debaromyces hansenii, Guignardia sp., Hypoxylon anthochroum, Meyerozyma caribbica, Paecilomyces lilacinus were found in leaf samples of H. brunonis. Alternaria alternata, Cunninghamella echinulata, Fusarium fusarioides, Fusarium oxysporum, Phanerochaete sp. were found in stem samples. Lasiodiplodia theobromae was commonly present in both the samples. The zone of inhibition by the endophytic fungi Curvularia pallescens isolated from H. brunonis for Candida albicans was up to 24 mm diameter, which is comparable to the inhibition by the antifungal standard Nystatin (24 mm). In seven endophytic fungi possessed free radical scavenging activity at 10 ¥ìg/ml, the highest being in C. pallescens extracts. In the present study, C. pallescens exhibited better antimicrobial and antioxidant activity compared to the other extracts. The presence of mycotoxin curvularin was reported in the partially purified fraction of C. pallescens.
KEYWORD
Fungal endophytes, Curvularia pallescens, Candida albicans, Antimicrobial
FullTexts / Linksout information
Listed journal information
ÇмúÁøÈïÀç´Ü(KCI)