|
KMID : 1200820180180030187
|
|
Oriental Pharmacy and Experimental Medicine
2018 Volume.18 No. 3 p.187 ~ p.197
|
|
|
Etiology of hepatocellular carcinoma and treatment through medicinal plants: a comprehensive review
|
|
Nasreen Sundas
Safeer Sobia
Dar Kamaran Khurshid
Andleeb Saiqa
Ejaz Mubashir
Khan Muhammad Adeeb
Ali Shaukat
|
|
|
Abstract
|
|
|
|
Liver is a power house of the body for many components such as vitamins, minerals, iron and glycogen and play role in biotransformation. Some ingredients of our diet (foodstuffs may contain with aflatoxin B1, vinyl chloride, tobacco, heavy alcohol intake, fried meat, coffee and oral contraceptives),when metabolized become tremendous for liver and leads toward hepatocellular carcinoma (HCC). HCC occurs through cyclical liver injury due to inflammation and DNA damaging as a result of oxidative stress. Phytochemicals of medicinal plants have curative potential against liver cancer due to presence of linalool, eucalyptol, borneol, thujone, camphor, 4-terpineol, monoterpenes and α-cadinol, sophytotherapies have several advantages over conventional chemotherapies. According to literature survey Acanthus ilicifolius, Allium sativum, Artemisiaprinceps, Artemisia vulgaris, Amorphophallus campanulatus, Brucea javanica, Broussonetia luzonica, Dracocephalum kotschyi, Graptopetalum paraguayense, Nigella sativa, Petasites japonicas, Silybum marianum, Bergenia ciliata, Cassia fistula and Picrorhiza scrophularilora have vital bioactive compounds used against hepatocellular carcinoma.
|
|
|
KEYWORD
|
|
|
Hepatocellular carcinoma, Diethylnitrosoamine, Anti-cancerous activity, Bergenia ciliata, Alpha fetoprotein
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|