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KMID : 1201620090020020088
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Journal of Women s Medicine
2009 Volume.2 No. 2 p.88 ~ p.91
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Uterine angiomyolipoma with partial cystic changes
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Cho Hye-Yon
Kim Hong-Bae
Kim Ki-Kyung
Lee Min-Jin
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Abstract
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Angiomyolipomas (AMLs) are neoplasms of renal origin, which are rare and almost always benign. Although extrarenal AMLs have been reported, only a few cases have been described involving the uterus. And no cases have been reported in Korea. We report an asymptomatic 62-year-old woman with an AML involving the uterus. Pre-operatively, the lesion was indistinguishable from a dermoid cyst on ultrasound and computed tomography (CT); however, at explorative laparotomy, a circumscribed intramural lesion involving the corpus uteri was found. Histologically, it was comprised of mature adipocytes with numerous intervening anomalous blood vessels and non-vascular smooth muscle cells. Immunohistochemical staining revealed that non-vascular smooth muscle cells were positive for α-smooth muscle actin (α-SMA), negative for antihuman melanoma (HMB-45), and the proliferating vessels were positive for CD34.
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KEYWORD
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Uterine angiomyolipoma, HMB45, α-SMA, CD34
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