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KMID : 1201620090020030095
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Journal of Women s Medicine
2009 Volume.2 No. 3 p.95 ~ p.99
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Recent trends in hormone therapy
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Kim Heung-Yeol
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Abstract
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The purpose of this review was to provide an update both clinicians and the lay public regarding the evidence-based position statement for menopausal hormone therapy (HT) with consideration for the therapeutic benefit-risk ratio at various times through the menopause. Current evidence supports a consensus regarding the role of HT in postmenopausal women when potential therapeutic benefits and risks around the time of menopause are considered. This review addresses all of these areas along with explanatory comments. Conclusions that vary from the 2008 position statement are highlighted. Addenda include a discussion of risk concepts, a new component not included in the 2008 paper, and a recommended list of areas for future HT research. Recent data support the initiation of HT around the time of menopause to treat menopause-related symptoms in an effort to treat or reduce the risk of certain disorders, such as osteoporosis or fractures in select postmenopausal women, or both. The benefit-risk ratio for menopausal HT is favorable close to the menopause, but decreases with aging and time sinc menopause in previously untreated women.
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KEYWORD
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Menopause, Hormone therapy, Benefit, Risk
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