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KMID : 1201620100030010012
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Journal of Women s Medicine
2010 Volume.3 No. 1 p.12 ~ p.17
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A clinicopathologic study of ovarian granulosa cell tumor
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Kwon Sang-Hoon
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Abstract
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Objective: This clinical study was to evaluate the patients’ clinical and pathological characteristics and treatment results in women with ovarian granulosa cell tumor.
Methods: A clinical study was made on 31 cases of ovarian granulosa cell tumor that were treated at the department of Obstetrics and Gynecology in the Keimyung University Dongsan Medical Center between January 1997 and December 2005. Clinical and pathological characteristics, treatment results, follow-up data for 31 women with granulosa cell tumor were collected retrospectively from medical records.
Results: The mean age of patients was 49 years (24 to 86 years). The chief complaints of patients were 18 cases of abdominal mass, 3 cases of abdominal discomfort, 3 cases of vaginal bleeding, 1 case of hemoperitoneum and 3 cases of no symptom. Bilaterality of mass was 2 cases, and mean size of tumor was 8.7 cm. 64.5% of patients were with FIGO stage I, 6.4% with stage II, 16.1% with stage III, and none with stage IV. Follow-up time was 5 years. The five year disease free survival rate was 93%. Significant prognostic factors were FIGO stage.
Conclusion: Even through granulosa cell tumor usually has good prognosis, it is a tumor of unquestionable malignant potential and has a tendency for late relapse. Long term follow-up is recommended.
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KEYWORD
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Granulosa cell tumor, Ovary
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