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KMID : 1204320070230040477
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Laboratory Animal Research
2007 Volume.23 No. 4 p.477 ~ p.480
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Pathological Study on Interstitial Pneumonia in Korean Native Goats
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Kim Ha-Hyun
Kim In-Joong
Hwang In-Jin
Park Sang-Ik
Jeong Young-Ju
Hyun Bang-Hun
Kwon Chang-Hee
Cho Kyoung-Oh
Park Su-Jin
Kang Mun-Il
Yang Dong-Kun
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Abstract
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The interstitial pneumonia of animal and human can be induced by various factors throughout the aerogenous and hematogenous routes. Although the causative agents of the interstitial pneumonia in the sheep and goats are known to be usually infectious agents, its prevalence in the Korean native goats is not well studied in South Korea. Therefore, pathological examination of interstitial pneumonia whose causative agents were unknown was performed with four neonatal goats obtained from four farms. These goats showed progressive depression and anorexia. At necropsy, diffuse depression of all lung lobules with some patch normal lobules were observed. On the cut surface, visible exudates were not observed in airways except for one case who had mild foamy materials in the bronchioles and bronchi. The pulmonary parenchyma had a meaty appearance. Histologically, alveolar walls were thickened by prominent hyperplasia of type Ⅱ pneumocytes with some macrophages. The lining epithelia of the bronchioles and bronchi were intact. From these results, these cases were diagnosed as interstitial pneumonia in the Korean native goats. Since many infectious agents cause interstitial pneumonia with the infiltration of lymphoid cells into alveolar wall and peribronchial regions, the findings observed in the present cases suggest the possibility that these pulmonary lesions may not be caused by infectious agents. Therefore, further studies will need to find out the precise causative agents from the lung lesions in the affected goats.
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KEYWORD
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Goat, interstitial pneumonia, type Ⅱ pneumocytes
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