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KMID : 1204320070230040481
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Laboratory Animal Research
2007 Volume.23 No. 4 p.481 ~ p.484
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Pulmonary Adenocarcinoma in a Dairy Goat Raised in Korea
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Kim Ha-Hyun
Cho Kyoung-Oh
Park Su-Jin
Kang Mun-Il
Yang Dong-Kun
Kim In-Joong
Hwang In-Jin
Park Sang-Ik
Hyun Bang-Hun
Kwon Chang-Hee
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Abstract
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Pulmonary adenocarcinoma was found in a 3-year-old dairy goat raised in Korea. At necropsy, a firm, greyish round neoplastic mass measuring approximately 1 ㎝ in diameter was detected in the left diaphragmatic lung lobe. Histologically, tumor lesions consisted of acini and papilla lined by short columnar and cuboidal epithelial cells. The stroma of tumors was thin and had mild lymphoid cell infiltration. Neutrophils and necrotic cell debri and/or mucus were densely compacted in the tumor acini. There were lymphoid cell aggregations in and around the tumor lesions. Mitotic figures were not detectable in the tumor lesions. No metastasis of this tumor was observed in any organs and tissues. From these results, this tumor was diagnosed as well differentiated adenocarcinoma in a dairy goat. This is the first report about pulmonary adenocarcinoma in goats raised in Korea. Since lung adenocarcinomas found in sheep and goats are mostly caused by betaretrovirus, the possibility of a retroviral etiology of this tumor will be evaluated in this article.
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KEYWORD
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Pulmonary adenocarcinoma, goat, betaretrovirus
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