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KMID : 1204320080240030453
Laboratory Animal Research
2008 Volume.24 No. 3 p.453 ~ p.455
Analysis of Body Composition Using the LaTheta, Experimental Animal Computer Tomography System
Shim Se-Hwan

Kwon Jung-Kee
Abstract
The aim of this paper is to report experimental animal computer tomography (CT) scanner, LaTheta, for in vivo experiments. The LaTheta CT scanner enables us to analyze several parameters such as body fat and bone measurement without any dissection and with minimum of radiation dose. In the present study we showed that LaTheta-based analysis allows the evaluation of fat volume and bone mineral density (BMD) in gad (UCH-L1 knockout) mice compare with wild-type mice. Male gad mice evidenced a significantly decreased cortical and spongy bone BMD rate in the femora. In summary, the LaTheta CT scanner is a new instrument that offers applicable methodology for quantitative analysis of body fat and various bone properties.
KEYWORD
Bone, fat, LaTheta, gad mice
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