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KMID : 1204320080240030461
Laboratory Animal Research
2008 Volume.24 No. 3 p.461 ~ p.467
New Establishment of International Animal Biosafety Level 3 Facility
Cho Yoon-Ju

Lee Young-Ah
Jhun Hyun-Jhung
Ham Ho-Suk
Ju Young-Duk
Han Jin-Soo
Abstract
As the use of laboratory animals has increased in Korea, the need for new facilities has also grown. Today, the increased risk of handling infectious microorganisms of animals could lead to an increase in contamination of the laboratory environment and personnel. The World Health Organization (WHO) has recognized that biosafety is an important international issue; in response, the organization published the third edition of the Laboratory Biosafety Manual, 2004. More recently, the Public Health Agency of Canada published its own biosafety document, the third edition of Laboratory Biosafety Guidelines, in 2004. Additionally, the U.S. Department of Health and Human Services published the fifth edition of its Biosafety in Microbiological and Biomedical Laboratories in 2007. The National Institutes of Health, the Korea Centers for Disease Control and Prevention (KCDC) updated its Guideline for Laboratory Biosafety, concerning biosafety facilities, in May 2007. We analyzed the A-BL facilities in Canada, Australia, Japan, and the U.S.A. to compare them with our circumstances here in Korea. The Laboratory Animal Research Center of Konkuk University (KULARC) has recently established the Animal Biosafety Level-3 facility (ABL3). To ensure whether the KULARC¡¯s A-BL3 facility was properly designed and built, we inspected it using a biosafety checklist to aid us in the process of uncovering latent defects in existing facilities, and we now believe that we have met the related guidelines. We are sure that this facility provides an excellent example to other institutions and organizations planning to build an A-BL3 facility.
KEYWORD
Biosafety, biosecurity, animal biosafety level 3
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