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KMID : 1204320080240040681
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Laboratory Animal Research
2008 Volume.24 No. 4 p.681 ~ p.683
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Spontaneous Ovarian Mucinous Adenocarcinama in a Mongolian Gerbil (Meriones unguiculatus)
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Hong Sun-Hwa
Lee Hyun-A
Kim Ok-Jin
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Abstract
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An ovarian mucinous adenocarcinoma was found in a 5-month-old female Mongolian gerbil (Meriones unguiculatus). The animal was evaluated because of slowly progressive abdominal enlargement. Postmortem examination revealed clear, pale, straw-colored fluid in the peritoneal cavity. The left ovary was very huge size as 2x5x3 cm and nodular shaped. Histologically, the tumor was composed of various sizes of multilocular cystic glands lined by a single layer of mucin-filled epithelium. Each of these cystic glands was surrounded by a large amount of solid fibrous stroma resembling smooth muscle. Also, undifferentiated tumor cells were found frequently. The ovarian surface epithelium showed partial invasiveness into the ovarian cortex, and a transition was observed between the surface epithelium and the mucinous cyst-forming epithelium. On the basis of histopathological findings, this case was diagnosed as an ovarian mucinous adenocarcinoma. To our knowledge, this report may be the first case of mucinous adenocarcinoma in Mongolian gerbil.
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KEYWORD
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Ovary tumor, mucinous adenocarcinoma, gerbil, animal
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