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KMID : 1204320090250010059
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Laboratory Animal Research
2009 Volume.25 No. 1 p.59 ~ p.64
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The Effects of Mixed Microorganism on Odor and Skin Irritation of Associated with Paraphenylenediamine
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Kim Hye-jin
Song Je-Ho
Kim Ok-Jin
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Abstract
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Hair dyes can cause skin irritation and malodorous smells. Paraphenylenediamine (PPDA) is a chemical substance that is widely used as a permanent hair dye. The reaction caused by the use of hair dyes, including PPDA, involves dermatitis. As a result, people that commonly work with PPDA, such as hairdressers, may develop dermatitis. Recently, the effective microorganism (EM) has revealed several beneficial effects. Therefore, this study was conducted to evaluate the reduction of hair dye irritation and odor by EM. An ammonia reduction study and skin irritation test was conducted using EM. The ammonia reduction study was performed using chromogenic gas detector tubes, and the skin irritation test was conducted using New Zealand white rabbits. Specifically, we applied PPDA with or without EM to the skin of the rabbits and then evaluated the irritation grades based on histopathological examination. The results of this study indicated that EM reduced the malodorous smell and skin irritation associated with the hair dyes evaluated in this study. These findings suggest that EM could be used to ameliorate the malodorous smell and skin irritation associated with hair dyes.
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KEYWORD
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Effective microorganism, odor, irritation, hair dye, paraphenylenediamine
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