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KMID : 1204320100260020127
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Laboratory Animal Research
2010 Volume.26 No. 2 p.127 ~ p.132
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Skin Whitening Effects of Sanguisorba officinalis and Stichopus japonicus
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Lee Min-Ok
Sul Jeong-Dug
Lee Hyun-A
Kim Ok-Jin
Oh Hong-Geun
Park Sang-Ho
Song Je-Ho
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Abstract
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This study is aimed to evaluate skin whitening effects of Sanguisorba officinalis and Stichopus japonicus for cosmeceutical ingredients. The extract of Stichopus japonicus showed 61.78% inhibition of tyrosinase activity, and the mixture of Sanguisorba officinalis extract and Stichopus japonicus extract showed 59.14% inhibition of tyrosinase activity. On the clone M-3 cell meloanocyte, the mixture of Sanguisorba officinalis extract and Stichopus japonicus extract showed remarkable inhibition of melanogenesis. Also, those extracts were not irritable in ocular irritation test. It is concluded from these results that Sanguisorba officinalis and Stichopus japonicus have skin whitening effect. It could be used as natural depigmental material in cosmeceutical ingredients.
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KEYWORD
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Sanguisorba officinalis, Stichopus japonicus, herb, skin whitening, depigment, cosmeceutical ingredient
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